A study published in the July issue of the Journal of Biological Chemistry finds that calorie restriction (mainly via a low carbohydrate diet) can reverse the pathologic changes that Alzheimer’s disease triggers in the brain.

The study showed that calorie restriction in mice reduced the amount of beta-amyloid in the brain. Accumulation of Beta-Amyloid is one of the main neuropathologic findings in Alzheimer’s disease.

There are actually several articles that have been published in the last several years arguing that a low carbohydrate diet may protect against and reverse Alzheimer’s disease:

• Emerging neuroprotective strategies for Alzheimer’s disease: dietary restriction, telomerase activation, and stem cell therapy.
• Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms.
• Calorie restriction may be neuroprotective in Alzheimer’s disease and Parkinson’s disease.
• Neuronal protection by sirtuins in Alzheimer’s disease

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