Prednisone is a corticosteroid, and neurologists typically prescribe it quite often, as many of the diseases we see respond dramatically to it.
Examples include multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), intractable migraines, as well as polymyositis. Other specialists like Rheumatologists and Pulmonologists also tend to frequently prescribe it for patients with arthritis and asthma.
Unfortunately, while reminding patients of prednisone's side effects (which are many!), not uncommonly most of us fail to tell them about memory loss.
Why is prednisone such a brain buster? Prednisone is a corticosteroid, a hormone that is directly toxic to the main memory engine of the brain- the hippocampus. In severe cases, a corticosteroid dementia can even develop.
Hope may be on the way though. Just read a study which utilizes gene therapy to transform a corticosteroid signal (which normally damages the hippocampus) into an estrogen-like signal (which has favorable effects on the hippocampus).


















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