About 2 weeks ago, I posted how an “empty stomach” can improve memory and boost brain power via a stomach-made hormone called ghrelin.
Ghrelin travels to the hippocampus, the memory engine of the brain, and causes new connections to form between brain cells.
Now, a study has been published that shows a low carbohydrate diet can reduce and reverse the pathologic signs of Alzheimer’s disease in mice.
The findings, out of the Mount Sinai School of Medicine in New York City, were published in the July issue of Journal of Biological Chemistry.
Both of these findings are consistent with the fascinating recent research done in the field of caloric restriction, which I’m going to post more about shortly.
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Re: “Now, a study has been published that shows a low carbohydrate diet can reduce and reverse the pathologic signs of Alzheimer’s disease in mice.”
I wouldn’t put too much stock in experiments on mice being relevant to humans. They’ve already cured certain cancers in mice, but the results were not transferable to humans. Researchers always promise a lot with their mice experiments, but fail to deliver since mice aren’t the same as us. Likewise, while most humans adore chocolate, it can be deadly to their pet dog. We have to focus more on human-applicable research.
Hi Michael. Thanks for stopping by.
Yes, what you say is true, one must be careful extrapolating results from mice to humans.
Nonetheless, many many studies have looked at how calorie restriction affects both brain and body, and findings overall seem to indicate a favorable effect will probably pan out in humans.
Whether it will actually reverse the pathologic changes of Alzheimer’s disease in humans is largely unknown.
My poor Mexican Hairless starts wimpering when I go breaking off a piece of chocolate to eat. Bad for their hearts, I think.
Hi Dr. Kaplan,
I was referring more to the low carbohydrate aspect of the article. As you mentioned, I’ve read that a low calorie diet promotes longevity in humans. Nevertheless, most of us seem to follow a high calorie diet. Another aspect relates to how nutritious foods are nowadays compared to yesteryear. Maybe some people feel they have to eat more to obtain the same nutrients. Anyway, certainly an interesting topic. Looks like you’ll have to enjoy your chocolate behind closed doors (lol).
[...] Eat Less, Remember More: Smartkit site. Caloric restriction can reverse memory loss? (Older news, but new to me). Check out other articles for executives here. [...]